William O'Connell
Seattle, WA | (206) 551-5524 | WilliamOConnellPMP@gmail.com | LinkedIn | Resume

Healthcare & Life Sciences Program Delivery · Regulated Systems · AWS CertifiedIT Program / Delivery Manager · Engagement Manager · TIPM · TPM · GxP · Cloud · AI Safety

Available: Healthcare & Life Sciences · IT Program/Delivery Manager · Engagement Manager · TIPM · TPM · GxP · Cloud · AI Safety · AWS SAA · PMP · Contract & FTE · Seattle / Remote

IT program and delivery leader with 20+ years across healthcare and life sciences (HCLS) — owning end-to-end delivery of regulated systems, data center transformations, and cloud migrations, including 15 years at Roche/Genentech (8.5 as consultant, 6.5 as Delivery Head). AWS Certified Solutions Architect, currently building production systems on AWS serverless and Bedrock. Available for contract and FTE roles in Seattle and remote.

My discipline: Safety controls and operational rigor are not compliance overhead — they are engineering requirements. That philosophy, developed across GxP-regulated systems where a missed control has patient consequences, applies equally to AI infrastructure where a degraded safety pipeline can be invisible and catastrophic. Two production examples: AI Safety & Guardrails for Enterprise Systems — deterministic guardrails on Amazon Bedrock, 640/640 OQ tests passed — and untangledthinking.org, a privacy-first recovery support tool on AWS serverless where user vulnerability made zero data retention a first-principle design decision. The result: zero unplanned downtime, zero compliance findings, delivery at scale.

Delivery Track Record:$100M+ DC delivery~25 infra projects/year23 TPMs (10 FTE) + 50 delivery resourcesResplan PM: eliminated overallocationColo & vendor delivery