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William O'Connell|Seattle, WA|(206) 551-5524|WilliamOConnellPMP@gmail.com|LinkedIn

Enterprise Cloud Delivery · Life Sciences & Regulated Environments · AWS Certified

20+ years of enterprise delivery at scale — including 15 years at Roche/Genentech (8.5 as consultant, 6.5 as Delivery Head). AWS Certified. Available for contract and FTE roles in Seattle and remote.

$100M+ Program Delivery·100K+ Users Migrated·25+ Concurrent Programs·$20M+ Annual Budget
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TIPM · TPM · Engagement Manager
Data Center Delivery · Cloud Migration · AWS Certified · $100M+ Programs
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AWS ProServe · Engagement Manager · HCLS
AWS Cloud Delivery · Life Sciences · GxP · 21 CFR Part 11 · Enterprise Consulting
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Anthropic · AI Safety Infrastructure · Enterprise Readiness · TPM
Regulated Systems · GxP Discipline · LLM Guardrail Architecture · AWS Bedrock · $100M+ Programs
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Three parallel efforts during 6.5 years as Delivery Head at Roche/Genentech:
NA & APAC Infrastructure Delivery Portfolio — continuous, year-over-year delivery of ~25 infrastructure projects annually across DC, network, contact center, middleware, modernization, IAM, and shared platforms on a $20–25M annual budget. Run by 10 FTE TPMs + 4 contract TPMs, supported by 50+ PMs, project coordinators, business analysts, and OCM specialists.
Data Center Program — directed a multi-year DC transformation delivered by 9 contract TPMs, including negotiating a colo SOW with enforceable penalty clauses that secured first-tenant status at a newly-built facility.
Resplan — Product Manager for an internal capacity-planning tool that effectively eliminated resource overallocation across the delivery portfolio.

Also led the OCM for a 100,000-user global migration to Google Cloud. In 2025 I completed a deliberate cloud and AI certification sprint, built two production AWS serverless systems, and deployed an AI Conversational Safety Layer on Amazon Bedrock and Claude with deterministic guardrails, RBAC enforcement, and structured audit logging. Both systems are live at this site.

Delivery at scale — the numbers

$25M annual portfolio. 25+ concurrent programs. 100+ direct resources. $100M+ program delivery. 100,000-user global migrations. Zero unplanned downtime across all delivery waves. Zero compliance findings across a $100M+ data center modernization.

That record was built at Roche/Genentech over 15 years — directing infrastructure transformation across data centers, cloud migrations, AWS IAM, enterprise platforms, and SaaS across North America and APAC. Eight of those years as an external consultant walking in cold and earning trust through delivery.

Risk mitigation as a discipline

Every program I have delivered is built on the same foundation: surface the risk before it surfaces as a finding. Build the control into the plan. Protect the outcome before the crisis arrives.

That discipline runs from GxP-regulated life sciences delivery — where a missed control has patient consequences — to AI guardrail architecture on Amazon Bedrock where a degraded safety pipeline can be invisible and catastrophic. Safety controls are engineering requirements. Not compliance overhead.

Current and hands-on in cloud and AI

AWS Certified Solutions Architect — Associate (Oct 2025, proctored exam). Production serverless platform built end-to-end on Cognito, Lambda, API Gateway, DynamoDB, and S3 — GxP-aligned, 21 CFR Part 11 compliant with full IQ/OQ/PQ validation lifecycle. Amazon Bedrock AI Conversational Safety Layer with deterministic guardrails, RBAC enforcement, and structured audit logging. Both live at this site.

Also developing a Recovery Pattern Recognition Tool using Claude API and AWS Lambda — targeting AI safety applications for vulnerable populations.